Restylane vs Juvederm

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People who are considering treatment for wrinkles, sagging skin, or just wish to gain a more youthful appearance want to make sure they choose the right option. Surgeons have their own preference, though most reviews and advice from plastic surgeons posted on the internet say the same thing: Restylane and Juvederm both perform well. In practice, the products are basically the same and provide the same effects.

Chemical Make-up

Both products are made from hyaluronic acid, a type of sugar that naturally occurs in the human body. Originally dermal fillers were made from bovine hyaluronic acids, but today both Restylane and Juvederm are created with non-animal components. Both products do not need allergy testing and can be used on consultation day if the patient chooses to go through with treatment. Both products should not be used on people that have had severe allergic reactions in the past or who are allergic to lidocaine as it is contained in the syringe to reduce pain.

The products are essentially the same, with only a few differences in chemical structure due to manufacturing processes.

Contour Creation

While both products provide fullness under the skin, reducing or eliminating the appearance of wrinkles or folds. Juvederm is more diffused when injected, and it spreads under the skin. Restylane is more cohesive and should be molded to achieve the best results. Some patients have complained that Restylane can leave lumps, but this is usually due to an unexperienced surgeon not ‘molding’ it under the skin properly.


The major difference between these products are price. Juvederm costs more per syringe than Restylane and offers less product per syringe. It takes more Juvederm to supply the same results as Restylane, which causes the treatments to be more expensive. The actual price may vary from office to office. Some surgeons may receive discounts on the product they use the most which can lead to a discount for patients.

Juvederm’s syringes must be used all in one treatment, as it cannot be capped and saved for later use. Restylane offers smaller syringe amounts so patients can choose to purchase a smaller syringe if they do not have a large amount of problems to be corrected.


Both Juvederm and Restalyne have results that are visible right away. Different patients have results that last for different lengths of time. Some patients have reported results that lasted over a year with both products. Due to how the body metabolizes hyaluronic acids, eventually both products smooth out and provide less volume. Regular injections can extend the efficiency and look over years.

Practitioner Choice

Every surgeon has his or her own preference between the two products. Both manufacturers offer programs for surgeons, such as discounts and listings on the manufacturer’s websites. Not all surgeons will rely on the programs for making a choice between products. Surgeons that do not use the programs to make a decision will base their choice on ease of use, results, and how they believe the product lasts.

Injection Ease and Behavior

Both products can be injected near the eye and other thin skin areas. Some surgeons prefer using Restylane near the eye due to the cohesive nature of the product. Juvederm may ‘drift’ away from the original area, as it spreads into the tissue more than Restylane. Juvederm may also cause a coloring effect near the eye, a blue tinge may show up in some patients. Juvederm has a needle that is ultra-fine, allowing greater accuracy of injection. Restylane can still be accurately placed, as it will not drift, though it will need molding in some applications.

If you’ve got questions about which is best for you, Dr. Michael Horn is happy to assist you. Your concerns are important to him and the entire staff.